Neighbour-joining tree of the 211 thaumatin domains of TLP subgroup I. Functionally characterized TLPs and corresponding functions are indicated. Poplar sequence names are in red. The 5 letter code before each protein ID corresponds to the 3 first letters of the genus name followed by the 2 first letters of the species name. The red arrow indicates PR-5d used for 3D structure alignment and black arrows indicate sequences used for alignment mapping on 3D Structure (see Figure 6). The red star indicates the Small-TLP-Kinase from Sorghum bicolor (Sb03g025670). The two columns successively indicate proteins with demonstrated antifungal activity and other functions. a: protection against abiotic stress; b: antifreeze activity; c: membrane permeabilization activity; d: xylanase inhibitor; e: α-amylase/trypsin inhibition; f: apoptosis-inducing in yeast; g: GPCR binding; h: CMV1-a binding; i: glycoprotein binding; j: endo-β-1,3-glucanase activity; k: solved 3D structures. References corresponding to these data are summarized in Additional file 8. Branch lengths are proportional to phylogenetic distances.