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Table 3 Hierarchical clustering of highly enriched genes using gene set enrichment score and kappa coefficient at molecular function. The kappa coefficient is the de facto standard to evaluate the agreement between raters, which factors out expected agreement due to chance. Kappa value: Very High (0.75–1), High (0.5–0.75), Moderate (0.25–0.5) and Low (< 0.25)

From: Comprehensive in silico analysis of the underutilized crop tef (Eragrostis tef (Zucc.) Trotter) genome reveals drought tolerance signatures

Cluster

Gene ID

Gene Name

Kappa value

Kappa value term

Cluster 1:

Enrichment Score: 1.33

4339974

dehydration-responsive element-binding protein 1C

0.83

Very high

4347620

dehydration-responsive element-binding protein 1A-like

0.8

Very high

4324418

dehydration-responsive element-binding protein 2A-like

0.695

High

4334553

NAC domain-containing protein 2-like

0.64

High

4344714

AT-hook motif nuclear-localized protein 23)

0.64

High

4324824

WUSCHEL-related homeobox 9-like

0.59

High

4330838

bZIP transcription factor 23-like

0.59

High

4326871

ocs element-binding factor 1

0.5

High

Cluster 2:

Enrichment Score: 0.78

4333169

uncharacterized

0.92

Very high

4333878

uncharacterized

0.85

Very high

4332352

uncharacterized LOC4332352

0.83

Very high

4339571

probable purine permease 4

0.78

Very high

4336249

protein NRT1/ PTR FAMILY 4.5

0.76

Very high

4340325

uncharacterized

0.76

Very high

4350916

uncharacterized LOC4350916

0.72

High

4345581

CHAPERONE-like protein of por1

0.71

High

4335799

photosystem I subunit O

0.71

High

4340300

protein nuclear fusion defective 4

0.7

High

4333501

protein Detoxification 29

0.62

High

107278728

rust resistance kinase Lr10

0.62

High

4329854

beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

0.58

High

4340585

RING-H2 finger protein ATL46

0.57

High

4337170

probable pectinesterase/pectinesterase inhibitor 13

0.46

Moderate

4342431

protein Ethylene-Insensitive 2-like

0.46

Moderate

4342173

potassium transporter 22-like

0.44

Moderate

4330248

aquaporin PIP1-1-like

0.41

Moderate

4338289

probable glycerol-3-phosphate acyltransferase 3

0.39

Moderate

4330049

probable aquaporin PIP2-2)

0.37

Moderate

4331194

aquaporin PIP 1–3-like

0.35

Moderate