Fig. 7

Protein–protein interaction of the candidate genes of the QTLs for LP and BW. Network nodes represent proteins with splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus. Colored nodes: query proteins and first shell of interactors; white nodes: second shell of interactors; Empty nodes: unknown proteins. 3D structure filled nodes: some 3D structures are known or predicted. Edges represent protein–protein associations. Associations are meant to be specific and meaningful (i.e., proteins jointly contribute to a shared function); this does not necessarily mean that they physically bind to each other. Known Interactions, blue: from curated databases; purple: experimentally determined. Predicted Interactions, green: gene neighborhood, red: gene fusions; indigo: gene co-occurrence; Others, yellow: textmining, black: co-expression, light purple: protein homology