Fig. 4

Venn diagrams of numbers of DEGs. a Upregulated in 1a relative to 0a and 1b (1a-up). b Downregulated in 1a relative to 0a and 1b (1a-down). c Upregulated in 1b relative to 0b and 1a (1b-up). d Downregulated in 1b relative to 0b and 1a (1b-down). 0b, basal region without culture; 1a, apical region after 1 week of culture; 1b, basal region after 1 week of culture (log FC > |1|, FDR < 0.01)