Fig. 6
From: Chromatin-remodeling factor CHR721 with non-canonical PIP-box interacts with OsPCNA in Rice
Putative working model for the functional role of OsPCNA and CHR721 (a) At normal conditions, the genomic DNA of microsporocytes suffered from various damages during meiosis. RPA1a recognizes the single strand and recruited CHR721 to the damage site by interacting with each other. OsPCNA with functions of recruiting DNA damage repair factors were recruited to damage sites possibly by interacting with CHR721 or other ways. After repairing, microsporocytes can divide normally. (b) When CHR721 lose its function, genomic instability led to repair retardants. So, we can detect DNA damage fragments and the cell cycle of microsporocytes being arrested. Some parts of cells with integrity chromatin can be divided normally.