Muscat and muscat-like aromatic mutants non-neutral substitutions. The amino acid sequence of the region of the Muscats and muscat-like aromatic mutants non-neutral substitutions is shown for various plant and bacterial DXS. Identical amino acids are shown in bold type and the mutations are indicated above the relevant position. The amino acid residues that are substituted in Chardonnay Musqué clone 44-60 Dijon (S272P), Muscats (K284N), Gewürztraminer, Siegerrebe (R306C) and the putative deletion of GVTKQ(285-289) in Chasselas Musqué co-localize next to the mutations (D302N) responsible for the variegated phenotype of Arabidopsis lvr111 mutant. Full species names and GenBank accession numbers are as follows: Plant - AtCLA1 (Arabidopsis thaliana, NP_193291), CaDXS (Capsicum annuum , O78328), AaDXS (Artemisia annua, AF182286), LeDXS (Lycopersicon esculentum, AF143812), ZmDXS (Zea mays, ABP88134), PaDXS (Picea abies, ABS50518), CrDXS (Catharanthus roseus, CAA09804), MpDXS (Mentha x piperita, AAC33513); Bacteria - DXS Chlamydomonas (CAA07554), DXS Bradyrhizobium (YP 001204249).