Plant microRNAs and their role in defense against viruses: a bioinformatics approach

BMC Plant Biology

Table 2 miRANDA scoring values for each screening

			Negative controls				Positive controls
	Screenings	Plant miRNAs vs Plant viruses	Animal miRNAs vs Plant viruses	Rand1 vs Plant viruses	Rand2 vs Plant viruses	Plant miRNAs vs Animal viruses	Plant miRNAs vs Control Targets
Free-folding Energy (kcal/mol)	min	-23.05	-23.01	-23.01	-23.02	-23.03	-23.01
	mean	-26.34	-27.22	-26.89	-26.07	-26.16	-28.5
	max	-43.99	-45.13	-39.87	-38. 88.88	-36.26	-45.25
	p value		0.290	0.091	0.184	0.173	0.0626
Identity (%)	min	0.66	0.58	0.68	0.64	0.61	0.7059
	mean	0.78	0.78	0.79	0.78	0.79	0.814
	max	0.94	1	0.94	0.94	0.94	1
	p value		0.784	0.212	0.548	0.323	0.0592
miRANDA score	min	114	96	107	87	109	126
	mean	158.8	142	147.8	142.5	142.4	167.9
	max	182	187	182	180	182	194
	p value		↓* <*0.001*	0.548	↓* <*0.001*	↓* <*0.001*	↑* <*0.001*
Z score	min	7.009	6.834	7.009	6.995	7. 102	7.200
	mean	8.815	8.003	7.967	8.004	8.413	9.001
	max	10.080	9.895	8.967	9.746	10.426	11.581
	p value		0.643	0.342	0.423	0.262	0.089

p values are the result of pairwise Wilcoxon test between each screening and the plant microRNAs vs Plant viruses screening, * significant differences α = 0.05, ↓ significantly lower, ↑ significantly higher

ISSN: 1471-2229