Table 1 List of upregulated and downregulated genes in combined stresses. Literature survey showing annotation from different studies. Data was curated manually
Annotation | Functional relevance studies | Reference | |
|---|---|---|---|
Upregulated in BPT5204 all stresses | |||
Os01g0106400 | Similar to Isoflavone reductase homolog IRL (EC 1.3.1.) | Oxidoreductase activity; Overexpression leads to tolerance to ROS in rice | Kim et al., 2009 |
Os01g0162500 | Leucine-rich repeat-containing N-terminal, protein | Stress (Cold and drought) tolerance in rice; Required for Xa-21 transcript expression and Xa-21 mediated immunity in rice against Xoo | Liao et al.; 2016; 2. Caddell et al., 2017 |
Os01g0844300 | Peptidylprolyl isomerase | Aids in protein folding | Shaw, 2002 |
Os02g0178800 | Glossy1(GL1) homolog | Cuticular wax biosynthesis, Drought resistance in rice | Islam et al., 2009 |
Os02g0323000 | Felis catus multi-drug resistance related (Fragment) | ATPase activity, ATPase-coupled transmembrane transporter activity and ATP binding | UNIPROT |
Os02g0820200 | Serine/threonine protein kinase | Involved in abiotic stress (salt and osmotic) tolerance in Arabidiopsis | Zang et al., 2016 |
Os03g0140400 | Cytochrome P450 protein CYP96B4 | Involved in growth regulation and drought stress response in rice | Tamiru et al., 2015 |
Os04g0266900 | Transketolase C-terminal-like domain containing protein | Acts as a regulatory molecule binding site | Pfam, InterPro |
Os06g0544100 | Tyrosine protein kinase domain containing protein | Abiotic stress (drought, heat, salt and sumergence) tolerance | Elangovan et al., 2020 |
Os07g0194100 | OSK2 | Play important role in the early stages of endosperm development in rice seeds | Takano et al., 1998 |
Os07g0674400 | Pollen Ole e 1 allergen/extensin domain containing protein | Pollen germination and pollen tube growth | Jimenez-Lopez et al., 2012 |
Os09g0472900 | Blight-associated protein p12 precursor | p12 is responsinle for systemic acquired resistance in citrus plants against citrus blight | Uniprot |
Os12g0133300 | Carbohydrate transporter/ sugar porter/ transporter | Involved in long distance transport of sucrose from source to sink where sugars are used or stored | Doidy et al., 2012 |
Os12g0454800 | Receptor-like serine/threonine kinase | Cytokinin signaling | Afzal et al., 2008 |
Upregulated in TN1 all stresses | |||
Os01g0858000 | WD40 repeat domain containing protein | Function as molecular hubs mediating supramolecular interactions, involved in plant cell wall biosynthesis; Histone modification, transcription regulation and signal transduction | Guerriera et al., 2015; Hu et al., 2018 |
Os02g0536300 | Leucine-rich repeat 2 domain containing protein | Initiate immune response in plants by sensing PAMP | Ng and Xavier., 2011 |
Os02g0599151 | Probable protein phosphatase 2C 17 | Regulate various plant signal transduction pathways (MAPK signalling and ABA signalling) | Rodriguez et al., 1998; Endo et al., 2018 |
Os03g0188100 | transparent testa 12 protein | encodes a multidrug secondary transporter-like protein required for flavonoid sequestration in vacuoles of the seed coat endothelium in Arabidopsis | Debeaujon et al., 2001 |
Os03g0305800 | Galactosyl transferase family protein | Biosynthesis of plant cell wall, synthesis of diverse secondary metabolites and modification of plant hormones | Cao et al., 2008 |
Os03g0332900 | Protein kinase, core domain containing protein | Central components in plant responses to environmental stresses such as drought, high salinity, cold, and pathogen attack | Wang et al., 2020 |
Os03g0448500 | Calcineurin B-like protein | Decoding Ca2 + signatures elicited by a variety of abiotic stresses | Cho et al., 2016 |
Os03g0575200 | Potassium transporter 1 (OsHAK1) | Positively regulates drought stress responses in rice | Chen et al., 2017 |
Os03g0785900 | Similar to Glutathione-S-transferase | Involved in abiotic stress response and heavy metal (Arsenic) detoxification | Kumar and Trivedi (2018) |
Os03g0820500 | Similar to WCOR719 | Involved in dynamic reorganisation of cytoskeleton during low temperature acclimatisation | Danyluk et al., 1996 |
Os04g0127500 | Serine/threonine protein kinase-related domain containing protein | Involved in abiotic stress (salt and osmotic) tolerance in Arabidiopsis | Zang et al., 2016 |
Os04g0416100 | Transcription factor E2F1 (E2F-1) | Expressed throughout the cell cycle, Elevates CDK levels and activity, even under hormone-free conditions | TAIR (The Arabidopsis Information Resource) |
Os04g0584300 | Similar to Catalytic/ protein phosphatase type 2C | Regulate various plant signal transduction pathways (MAPK signalling and ABA signalling) | Rodriguez et al., 1998; Endo et al., 2018 |
Os05g0576800 | Blast and wounding induced mitogen-activated protein kinase | Activate MAPK pathway | Cheong et al., 2003 |
Os06g0191900 | Serine threonine kinase | Act as receptors for external factors like environmental conditions and mediate cellular responses | Afzal et al., 2008 |
Os06g0229000 | FtsH protease (VAR2) (Zinc dependent protease) | Involved with abiotic (light) stress response in Arabidopsis | Lopes et al., 2018 |
Os06g0275000 | Zinc finger protein, Heading date | Involved in abiotic stress tolerance | Jin et al., 2018 |
Os06g0681200 | Cupredoxin domain containing protein | Involved in abiotic stress responses | Jangam et al., 2016 |
Os06g0702100 | Methyl-CpG DNA binding domain containing protein | Involved in DNA methylation and abiotic stress responses | Parida et al., 2018 |
Os07g0175600 | Plant lipid transfer protein and hydrophobic protein, | Act as defense proteins in plant innate immunity, bind and transfer lipids and constitute one of the most clinically important classes of plant allergens | Finkina et al., 2016 |
Os07g0521500 | NB-ARC domain containing protein | Regulate the activity of R protein | Ooijen et al., 2008 |
Os07g0614300 | Von Willebrand factor type A domain containing protein, | Component of C-terminus of Lagging Growth and Development 1 (LGD1) and is responsible for the nuclear targeting and RNA binding activity | Thangasamy et al., 2012 |
Os10g0471000 | Protein of unknown function DUF810 | Involved in tolerance to drought and salt stress | Li et al., 2018 |
Os10g0521000 | TRE1 protein (Fragment) | Required for glycogen metabolism | Zhang et al., 2021 |
Os10g0529700 | glutathione transferase35 | Involved in abiotic stress response and heavy metal (Arsenic) detoxification | Kumar and Trivedi, 2018 |
Os11g0201400 | Histone deacetylase | Negatively regulates plant innate immunity by modulating histone H4 acetylation of defense-related genes in rice | Ding et al., 2012 |
Os11g0693800 | ATP-citrate synthase | Negatively regulates plant innate immunity in rice | Ruan et al., 2018 |
Os12g0512100 | Sugar/inositol transporter domain containing protein | Involved in transport of sugar from source to sink | Kong et al., 2019 |
Downregulated in BPT in all stresses | |||
Os02g0226200 | HAD-superfamily subfamily IB hydrolase, hypothetical 1 protein | Involved in intracellular or extracellular organic phosphorous recycling under inorganic phosphorous stress conditions in plants | Du et al., 2021 |
Os02g0249300 | Zinc finger, RING/FYVE/PHD-type domain containing protein | Involved in abiotic stress (salt and osmotic) tolerance in Arabidiopsis | Zang et al., 2016 |
Os03g0181750 | ABC transporter, transmembrane domain domain containing protein | Required for normal plant development, detoxification and pathogen defense via the transport of xenobiotics and secondary metabolites across the plants | Hwang et al., 2016 |
Os04g0364800 | Barwin-related endoglucanase domain containing protein | Aids in polysaccharide binding and Bawin is a putative plant defense protein; 2. All PR-4 proteins have Barwin domain | Todd et al., 2002; Franco et al., 2019 |
Os04g0385600 | Tetratricopeptide-like helical domain containing protein | involved in plant stress (osmotic stress) and hormone signalling (abscisic acid) | Schapire et al., 2006; Sharma and Pandey, 2016 |
Os04g0618700 | Protein kinase, core domain containing protein | Central components in plant responses to environmental stresses such as drought, high salinity, cold, and pathogen attack | Wang et al., 2020 |
Os04g0686000 | Zinc finger, RING/FYVE/PHD-type domain containing protein | Involved in abiotic stress (salt and osmotic) tolerance in Arabidiopsis | Zang et al., 2016 |
Os05g0170600 | CLE family OsCLE503 protein | Regulate cell proliferation and differentiation in plant shoots, roots, vasculature, and other tissues | Li et al., 2019 |
Os07g0162700 | Alpha/beta hydrolase fold-3 domain containing protein | Associated with housekeeping roles that participate in the breakdown and recycling of cellular metabolites, processing of external nutrients and detoxification of xenobiotics | Gershater and Edwards, 2007 |
Os08g0113000 | Peroxidase 47 precursor (EC 1.11.1.7) (Atperox P47) (ATP32) | Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress | UniProt (Reviewed) |
Os10g0376400 | Phosphate-induced protein 1 conserved region containing protein | Respond to abiotic stress (drought, cold, heat and salt) | Quan et al., 2018 |
Os10g0409400 | beta subunit of polygalacturonase 1, | Abiotic stress response, Cell wall formation and abiotic stress response | Liu et al., 2013 |
Os10g0508700 | Pectinesterase inhibitor domain containing protein | Control the activity of Pectin Methyl Esterase | Marzin et al., 2016 |
Os11g0300700 | Protein kinase domain | Central components in plant responses to environmental stresses such as drought, high salinity, cold, and pathogen attack | Wang et al., 2020 |
Downregulated in TN1 in all stresses | |||
Os01g0311600 | Sulfotransferase family protein | Respond to abiotic stress in rice; Asociated with drought, salt and ABA stress in chinese cabbaga | Chen et al., 2012; Jin et al., 2019 |
Os01g0823100 | Alpha-expansin OsEXPA2 | Involved in stem elongation; important for seed germination | Marowa et al., 2016; Huang et al., 2000 |
Os01g0871600 | Peptide transporter PTR2-B | Various role in rice development mainly in grain filling and germination stages, Also upregulated upon drought and salt stresses | Ouyang et al., 2010 |
Os01g0953400 | NB-ARC domain containing protein | Regulate the activity of R protein | Ooijen et al., 2008 |
Os02g0538400 | Armadillo-like helical domain containing protein | Role in plant development and abiotic stress signalling | Sharma et al., 2014 |
Os02g0616300 | Similar to Protein argonaute MEL1 | Development of pre-meiotic germ cells and the progression of meiosis | Komiya et al., 2014; UniProt |
Os03g0250200 | TB2/DP1 and HVA22 related protein family protein | Inhibits gibberllin mediated PCD, involved in vesicular trafficking | Guo and Ho, 2008 |
Os04g0541100 | Similar to Gt-2 | Probable glycosyl transferase, required for cell wall synthesis | Cao et al., 2008 |
Os05g0469800 | Pyruvate decarboxylase | Enzyme involved in alcohol fermentation, Also when overproduced enhance submergence tolerance in rice | Quimio et al., 2000 |
Os05g0477600 | Alpha-expansin OsEXPA4 | Internode elongation, Cell wall organisation in plants | Choi et al., 2003; |
Os05g0488000 | Peptidase C1A, papain family protein | Role in seed development and stress tolerance | Wang et al., 2018 |
Os05g0552400 | Zinc finger, RING/FYVE/PHD-type domain containing protein | Involved in abiotic stress (salt and osmotic) tolerance in Arabidiopsis | Zang et al., 2016 |
Os06g0142300 | Early nodulin 93 ENOD93 protein family protein | Candidate gene for brown plant hopper resistance in herbicide resistant rice; Required for somatic embryogenesis in oil palm | Wang et al., 2015; Chan et al., 2020 |
Os06g0179000 | Glycoside hydrolase family 79, N-terminal protein | Response to biotic and abiotic stresses, defense against herbivores, activation of phytohormones, lignification, and cell wall remodelling | Opassiri et al., 2006 |
Os06g0549900 | FAD linked oxidase, N-terminal domain containing protein | Required for the import and folding of small cysteine-containing proteins in the mitochondrial intermembrane space | UniProt |
Os06g0610800 | Peptidase A1 domain containing protein. Aspartic proteinase nepenthesin-1 | Aspartic-type endopeptidase activity. Involved in biotic and abiotic stress responses | 1.UniProt (reviewed); 2. Figueirido et al., 2021 |
Os07g0648000 | Armadillo-like helical domain containing protein | Role in plant development and abiotic stress signalling | Sharma et al., 2014 |
Os08g0442400 | BABY BOOM | Key regulators of plant cell totipotency. Induce somatic embryogenesis | Jha and Kumar, 2018; Khanday et al., 2020 |
Os08g0473900 | 1,4-alpha-D-glucan glucanohydrolase | Important for breakdown of endosperm starch during germination | UniProt; Guttikonda et al., 2020 |
Os08g0507100 | Cytochrome P450 family protein | Function in development regulation and drought stress response | Wei and Chen, 2018 |
Os09g0241700 | Homeodomain-like containing protein | Negative regulators in abiotic stress responses; Play role in reproductive development and abiotic stress signaling in rice | Bhattacharjee et al., 2016; Jain et al., 2008 |
Os09g0451400 | ACC oxidase | Ethylene biosynthesis | Lee and Yoon, 2018 |
Os10g0109900 | Major facilitator superfamily, general substrate transporter domain containing protein | Transport small compounds across biological membranes. Cadmium transporters in rice | Drew et al., 2021, Nino-Gonzalez et al., 2019; Yan et al., 2019 |
Os10g0556100 | beta-expansin EXPB4 | Internode elongation in rice | Lee et al., 2001 |
Os11g0212900 | Serine/threonine protein kinase-related domain containing protein | Involved in abiotic stress (salt and osmotic) tolerance in Arabidiopsis | Zang et al., 2016 |
Os11g0508600 | Sugar transporter | TAL effector-mediated susceptibility to bacterial pathogen (Xanthomonas) | Teper and Wang, 2021 |
Os11g0598300 | NB-ARC domain containing protein | Regulate the activity of R protein | Ooijen et al., 2008 |
Os11g0672300 | Protein kinase domain containing protein | central components in plant responses to environmental stresses such as drought, high salinity, cold, and pathogen attack | Wang et al., 2020 |
Os11g0675200 | NB-ARC domain containing protein | Regulate the activity of R protein | Ooijen et al., 2008 |
Os11g0676200 | NBS-LRR-like protein NBA2 (Fragment) | Component of R protein, Induce effector triggered immunity | DeYoung and Innes, 2006; Sagi et al., 2017 |
Os12g0569800 | Heat shock protein 70 | Involved in macromolecular translocation, carbohydrate metabolism, innate immunity, photosystem II repair and regulation of kinase activities | Wang et al., 2014 |
Os12g0637400 | Purple acid phosphatase (EC 3.1.3.2) | Inorganic Phosphorous remobilization from senescing to non-senescing leaves and organic Phosphorous utilization | Gao et al., 2017 |