Fig. 10From: Transcription-associated metabolomic profiling reveals the critical role of frost tolerance in wheatTranscript and metabolic profiling of significantly differential metabolites and DEGs in flavonol biosynthesis pathway in wheat under cold treatment. A The map of integrative analysis in flavonol biosynthesis metabolites and their biosynthesis-related key enzymes. Red font: significantly up-regulated differential metabolites or DEGs encoding the corresponding enzyme; green font: significantly down-regulated differential metabolites or DEGs encoding the corresponding enzyme; Blue font: significantly up/down-regulated DEGs encoding the corresponding enzyme; Black font: the enzyme encoding genes and differential metabolites detected but with no significant difference. Black arrow lines: ko00940; Blue arrow lines: ko00941; Red arrow lines: ko00944. DEGs and DAMs were investigated using the Kyoto Encyclopedia of Genes and Genomes (KEGG) to map to the possible KEGG pathway maps for the biological interpretation of systemic functions (www.kegg.jp/kegg/kegg1.html). B Heatmap of differential metabolites accumulation flavonol biosynthesis pathway. The color bar presented at the top right represents the level of metabolites, where red indicates the metabolites with a higher level, and blue indicates metabolites with a lower level. C Heatmap of DEGs enriched flavonol biosynthesis pathway. Gene expression was scaled using normalized FPKM for the mean value of three biological replicates. A color bar was presented at the top right, and the colors from blue to red indicate low to high expression. 4CL, 4-coumarate--CoA ligase; ANS, anthocyanidin synthase; CHI, chalcone isomerase; CHS, chalcone synthase; CYP73, trans-cinnamate 4-monooxygenase; CYP75B1, flavonoid 3′-monooxygenase; CYP93B2_16, flavone synthase II; CYP98, 5-O-(4-coumaroyl)-D-quinate 3′-monooxygenase; FG2, Kaempferol-3-O-rutinoside; FLS, flavonol synthase; HCT, shikimate O-hydroxycinnamoyltransferase; PAL, phenylalanine ammonia-lyase; UGT73C6, flavonol-3-O-L-rhamnoside-7-O-glucosyltransferase; CSE, caffeoyl shikimate esteraseBack to article page