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Table 3 Modules obtained following weighted correlation network analysis (WGCNA), their gene contents, and selected KEGG enrichment

From: Pathogen and drought stress affect cell wall and phytohormone signaling to shape host responses in a sorghum COMT bmr12 mutant

Module Label

Number of genes

Selected KEGG enrichment

Turquoise

1105

Photosynthesis, central metabolism, starch and sucrose metabolism, peroxisome

Blue

842

Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum, One carbon pool by folate, mRNA surveillance pathway, Histidine metabolism, RNA transport

Brown

666

Spliceosome, ubiquitin mediated proteolysis, proteasome, RNA transport, base excision repair

Yellow

665

Spliceosome, RNA transport

Green

594

Plant-pathogen interaction (ETI)

Red

550

Primary metabolism, proteasome, phagosome, ER protein processing, alpha-linolenic acid metabolism, phenylpropanoid biosynthesis

Black

545

Plant hormone signal transduction (primarily JA), aminoacyl-tRNA biosynthesis

Pink

539

Plant hormone signal transduction (primarily IAA and ABA), ubiquitin mediated proteolysis, mRNA surveillance pathway

Magenta

536

Ribosome, central metabolism, amino acid biosynthesis, RNA transport

Purple

511

Primary metabolism, phagosome

Green-yellow

454

Starch and sucrose metabolism

Tan

454

Spliceosome, peroxisome

Salmon

450

Phenylpropanoid metabolism

Cyan

405

Endocytosis

Midnight blue

381

Phenylpropanoid biosynthesis, glutathione metabolism, glycosaminogen degradation, ubiquinone and other terpenoid-quinone biosynthesis

Light cyan

358

Significant annotated KEGG enrichment not detected

Grey60

348

Ribosomal proteins, primary metabolism, amino acid biosynthesis, RNA polymerase

Light green

344

Flavonoid biosynthesis [six chalcone isomerase paralogs], proteasome, fatty acid degradation, glutathione metabolism, peroxisome, protein processing in the ER

Light yellow

319

Plant hormone signal transduction (ARF, DELLA, COI, MPK6)

Royal blue

251

Circadian rhythm, thiamine metabolism, protein export

Dark red

249

Significant annotated KEGG enrichment not detected

Dark green

245

Gly/Ser/Thr metabolism

Dark turquoise

232

Significant annotated KEGG enrichment not detected

Dark grey

230

Selenocompound metabolism, ribosome, phosphatidylinositol signaling

Orange

217

N-glycan metabolism, sphingolipid metabolism, unfolded protein response-related proteins

Dark orange

207

N glycan biosynthesis, sphingolipid metabolism, purine metabolism, protein processing in the ER

White

202

primary metabolism, propanoate metabolism, beta-alanine metabolism, fatty acid degradation

Sky blue

201

Significant annotated KEGG enrichment not detected

Saddle brown

197

protein processing in the ER/plant pathogen interaction (same set of genes, Hsp70 family)

Steel blue

174

Ribosome biogenesis

Pale turquoise

170

Spliceosome, RNA transport, and basal transcription factors

  1. Modules calculated by WGCNA revealed coexpression patterns enriched for annotated KEGG pathways