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Fig. 5 | BMC Plant Biology

Fig. 5

From: Crystal structure of DRIK1, a stress-responsive receptor-like pseudokinase, reveals the molecular basis for the absence of ATP binding

Fig. 5

ZmDRIK1-KD binds the small molecule ENMD-2076. a Thermal shift assay of ENMD-2076 binding to ZmDRIK1-KDR187-S514, as determined by DSF. The compound stabilization is shown by the dislocation of the protein thermal denaturation midpoint (Tm) in the presence of ligand versus in DMSO only (red line). b Chemical structure of the ENMD-2076 molecule. c Determination of the thermal dynamic properties of the ENMD-2076 interaction with ZmDRIK1-KDR187-S514 by ITC

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BMC Plant Biology

ISSN: 1471-2229

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