Fig. 2

Overview of structures. Key residues are shown in stick presentation, substrate molecule in ball-and-stick model, and heme molecule as spheres. Single-letter abbreviations for the amino acid residues are as follows: C, Cys; H, His; T, Thr; Q, Gln; R, Arg; E, Glu; and F, Phe. a Superposition of 4LXJ, TaCYP51G3_2D and ZmCYP51G35. Lanosterol molecule is shown in ball-and-stick model. The RMSD between the 4LXJ and TaCYP51G3_2D is 0.122 Å. The RMSD between the 4LXJ and ZmCYP51G35 is 0.162 Å. b Superposition of 2RCH, TaCYP74A98_4A and ZmCYP74A39. The RMSD between the 2RCH and TaCYP74A98 is 0.107 Å. The RMSD between the 2RCH and ZmCYP74A39 is 0.082 Å. c Superposition of 2X2N, TaCYP97A59_6B and ZmCYP97A16. The RMSD between the 2X2N and TaCYP97A59 is 0.178 Å. The RMSD between the 2X2N and ZmCYP97A16 is 0.151 Å. POSACONAZOLE molecule is shown in ball-and-stick model. SRS1–6: six putative SRS (substrate recognition sites) regions which are involved in recognition and binding of substrates according to Gotoh’s predicted models