Table 2 Parameters in the site analysis, branch and branch-site analyses of NADP-ME-B

Site analysis

–

M0:(one-ratio)

0.081

ω = 0.081

–

–

–

–

M3:(discrete)

0.088

p₀ = 0.468 ω₀ = 0.012

4

0.000 (M0 vs M3)

–

p₁ = 0.415 ω₁ = 0.091

p₂ = 0.117 ω₂ = 0.376

Branch analysis

–

M0

–

ω = 0.081

–

–

–

–

b1

–

ω0 = 0.081 ω₁ = 0.016

1

0.0254

–

–

b2

–

ω₀ = 0.081 ω₁ = 0.072

1

0.8415

–

–

b3

–

ω₀ = 0.081 ω₁ = 0.031

1

0.0495

–

–

b4

–

ω₀ = 0.081 ω₁ = 0.102

1

0.858

–

–

b5

–

ω₀ = 0.081 ω₁ = 0.112

1

0.5052

–

Branch-site analysis

–

M1

–

p0 = 0.912 p1 = 0.088

–

–

–

b1

Model A

–

p₀ = 0.862 p₁ = 0.083 (p_2a + p_2b = 0.055)

2

<  0.0001 (ModelA vs M1)

Prob > 0.6 (28R^a, 59 L^a, 108 V^a, 125R, 144 T, 169 L, 181S^a, 204 L)

ω₂ = 37.343

b2

Model A

–

p₀ = 0.912 p₁ = 0.088 (p_2a + p_2b = 0.000)

2

1.0000 (ModelA vs M1)

Prob > 0.6 (NO)

ω₂ = 1.000

b3

Model A

–

p₀ = 0.906 p₁ = 0.088 (p_2a + p_2b = 0.006)

2

0.1564 (ModelA vs M1)

Prob > 0.6 (59 L^a, 182 L)

ω2 = 19.072

b4

Model A

–

p₀ = 0.831 p₁ = 0.080 (p_2a + p_2b = 0.089)

2

0.3852 (ModelA vs M1)

Prob > 0.6 (NO)

ω2 = 3.081

b5

Model A

–

p0 = 0.895 p1 = 0.0.087 (p2a + p2b = 0.018)

2

0.0518 (ModelA vs M1)

Prob > 0.6 (59 L, 63S, 86E^a, 108 V, 181S)

ω₂ = 11.224