Fig. 4

The reprogramming of amino acid metabolism affected by methionine sulfoximine (MSX) treatment. The length of each column indicates the relative intensity which represents the content of each detected metabolite. Metabolites in grey font were not detected in this study. The schematic flowchart showing the biosynthesis of 20 proteinogenic amino acids was drafted according to Coruzzi et al. (2015). Red asterisks indicate statistically significant differences between MSX and CK groups (*P < 0.05 in student’s t-test)