Fig. 9

Identification of gene networks unique to mesotrione resistance associated with the GO terms gluconeogenesis, cytoskeleton organization and trehalose biosynthesis. We took advantage of the waterhemp (Amaranthus tuberculatus) annotation platform to identify the best Arabidopsis thaliana homologs for 91 unique resistant DETs associated with these GO terms. Forty-five unique A. thaliana identifiers were then submitted to the STRING website to identify potential gene networks [71]. All 45 unique A. thaliana identifiers were present in the database and 36 could be combined in a single network. Lines linking proteins indicate connections between proteins. The numbers in parentheses indicate the number of unique resistant DETs that correspond to each Arabidopsis gene ID. The yellow nodes highlight genes that have associations with dinitroaniline (HG 3) herbicide resistance, the purple node highlights an association with 2,4-D (HG 4) herbicide resistance, the orange nodes highlight associations with atrazine (HG 5) herbicide resistance and the green nodes highlight associations with paraquat (HG 22) herbicide resistance. The blue node highlights the only node in this network that interacted with all six nodes associated with herbicide resistance