Meiotic stage | Duration in CS (hour)a | Key events | No. of meiocytes isolated per hour, per person using the MeioCapture methodb | Condition of SACs |
---|---|---|---|---|
Pre-meiotic G2 | – | DNA replication and chromosome organization | 500 to 700 | Intact |
Leptotene | 10.4 | Chromosome association | 1000 to 1200 | Intact |
Zygotene | 3.4 | Homologue pairing and SC formation | 1000 to 1200 | Intact |
Pachytene | 2.2 | Crossing over and bivalent formation | 1400 to 1500 | Intact |
Diplotene | 0.6 | Dissociation of SCs | 1500 | Intact |
Diakinesis | 0.4 | Nuclear membrane disintegration and end of prophase I | 300 to 400 | Starting to disintegrate |
Metaphase I | 1.6 | Chromosomes line up on metaphase plate | 700 to 800 | Partially disintegrated |