Fig. 2

Solution NMR structures of jS3. a Superposition of the 20 lowest energy ensembles of jS3. b The ribbon NMR representation of jS3, which consists of three anti-parallel β-strands and a disulfide connectivity of CysI−CysV (yellow), CysII−CysIV (red) and CysIII−CysVI (blue). c The surface topology comparison between jS3 and jS1. Distribution of electrostatic charges was represented by blue (positively charged), red (negatively charged) and green (hydrophobic residues such as Val, Trp, Ile and Leu)