Fig. 4

Significantly overrepresented 3′ extensions of the CArG-box core. Enrichment of extensions of 3 nucleotides is calculated as the frequency of the extension after the CC(A/T)₆GGN-core in ChIP-seq peaks divided by the expected frequency of the extension based on the frequencies of nucleotides in the ChIP-seq peaks. All extensions are depicted for which at least one dataset is significant at p < 0.05. For visualization purposes, all extensions that are enriched relative to what is expected from nucleotide frequencies, but are not significant, are set to 1. Note that a similar analysis, but for CArG-box like sequences picked up by MEME-ChIP, is presented in Additional file 15: Table S7