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Table 4 KEGG pathway enrichment of genes showing dominance or transgressive regulation in hybrid

From: Transcriptomic analysis reveals overdominance playing a critical role in nicotine heterosis in Nicotiana tabacum L.

Genetic hypotheses

Regulation pattern

KEGGID

Count

Size

Term

Padjust

Dominance

Down

970

15

24

Aminoacyl-tRNA biosynthesis

0.000828

 

UP

940

69

155

Phenylpropanoid biosynthesis

7.87E-07

  

909

16

27

Sesquiterpenoid and triterpenoid biosynthesis

0.004545

  

360

21

41

Phenylalanine metabolism

0.005072

Overdominance

Down

630

32

80

Glyoxylate and dicarboxylate metabolism

9.57E-16

  

30

15

64

Pentose phosphate pathway

0.000399

  

51

11

46

Fructose and mannose metabolism

0.003397

  

670

5

10

One carbon pool by folate

0.003452

  

730

4

7

Thiamine metabolism

0.00693

 

UP

960

16

29

Tropane, piperidine and pyridine alkaloid biosynthesis

4.65E-08

  

940

36

155

Phenylpropanoid biosynthesis

3.09E-06

  

1230

34

174

Biosynthesis of amino acids

0.00028

  

531

5

7

Glycosaminoglycan degradation

0.002295

  

760

7

15

Nicotinate and nicotinamide metabolism

0.002986

  

61

10

33

Fatty acid biosynthesis

0.007455

  

945

8

23

Stilbenoid, diarylheptanoid and gingerol biosynthesis

0.009065

  

450

6

16

Selenocompound metabolism

0.019903

  

460

9

33

Cyanoamino acid metabolism

0.019903

  

620

14

67

Pyruvate metabolism

0.020196

  

780

5

12

Biotin metabolism

0.022967

  

904

4

8

Diterpenoid biosynthesis

0.026009

  

270

14

72

Cysteine and methionine metabolism

0.029642

  

950

6

19

Isoquinoline alkaloid biosynthesis

0.033853

  

750

4

9

Vitamin B6 metabolism

0.036257

  

253

3

5

Tetracycline biosynthesis

0.038749

  

604

2

2

Glycosphingolipid biosynthesis - ganglio series

0.044164