BMC Plant Biology

Table 2 Mutations severely affecting protein function as predicted by the PARSESNP and SIFT programs^a

From: Genetic analysis of phytoene synthase 1 (Psy1) gene function and regulation in common wheat

Gene	Mutant	Cultivar	Nucleotide change^b	Amino acid change^c	PSSM	SIFT
Psy-A1	M091151	J22	G1230A	R174K	16.2	0.03
Psy-D1	M090628	J20	C4110T	P409L	18	0.04
Psy-A1	M090158	J20	C3201T	Q346*
Psy-A1	M090950	J22	G1224A	W172*
Psy-A1	M091949	J22	C349T	Q117*

^aHigh PSSM (>10) and low SIFT scores (<0.05) predict mutations with severe effects on protein function. PSSM and SIFT scores are not reported for mutations that produce premature termination codons
^bThe first letter indicates the wild type nucleotide, the number is the position from the start codon, and the last letter is the mutant nucleotide
^cThe first letter indicates the wild type amino acid, the number is the position from the methionine, and the last letter is the mutant amino acid

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ISSN: 1471-2229

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