Fig. 8

Hierarchical cluster analysis and functional protein interaction networks of cold acclimation-induced reprogramming. a Hierarchical clustering of Arabidopsis accessions, acclimation states, and metabolite, protein and phosphopeptide abundances based on Euclidean distances. Columns represent non-cold acclimated (na) and cold-acclimated (acc) samples of Rsch and Cvi. Rows represent metabolites, proteins and phosphopeptides. Blue rectangles indicate the characteristic compounds which were chosen for reconstruction of the cold-acclimation induced interaction networks (part (b) and (c)). b Protein-protein interaction network of all proteins and phosphoproteins which were found to be involved in the cold acclimation-induced reprogramming of Rsch. c Protein-protein interaction network of all proteins and phosphoproteins which were found to be involved in the cold acclimation-induced reprogramming of Cvi. Interaction networks were created using the STRING database for known and predicted protein-protein interactions (setting: highest confidence (0.9); http://string-db.org/) [85]. A detailed list of protein-protein interactions for both accessions is provided in the supplement (Additional file 9: Table S6 and Additional file 10: Table S7)