Fig. 8From: The ARGOS gene family functions in a negative feedback loop to desensitize plants to ethyleneModel for negative feedback loop by which the ARGOS family desensitizes ethylene signaling. Key signaling elements of the ethylene pathway are shown, initial elements being localized to the endoplasmic reticulum (ER), the EIN3 transcription factor family being localized to the nucleus. Ethylene activates the transcriptional response to ethylene, stimulating expression of ARGOS family members. ARGOS family proteins insert into the ER where they serve to desensitize the ethylene signal outputBack to article page