Fig. 5

Expression profiles of transcripts encoding enzymes involved in ginsenoside biosynthesis in P. ginseng. Enzymes functioning in each step of the MVA and MEP pathways are indicated by bold letters. The expression patterns of transcripts encoding these enzymes are shown in the heatmap, which was constructed using average FPKM values obtained from individual FPKM values of three replicates. a indicates one-year-old whole roots and b, c, and d represent main bodies, lateral roots, and rhizomes of six-year-old root samples, respectively. The number of transcripts identified is shown in parentheses to the left of heatmap. AACT, acetyl CoA acetyltransferase; Beta-AS, beta-amyrin synthase; CDP-MEK, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; DS, dammarenediol II synthase; DXR, 1-deoxy-D-xylulose-5-phosphate reductoisomerase; FPS, farnesyl diphosphate synthase; GPS, geranylgeranyl diphosphate synthase; HMBPPR, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; HMBPPS, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; HMGR, 3-hydroxy-3-methylglutaryl-coenzymeA reductase; HMGS, hydroxymethyl glutaryl CoA synthase; IDI, isopentenyl-diphosphate delta-isomerase; MECDPS, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; MEP-CT, 2-C-methyl-D-erythritol4-phosphate cytidylyltransferase; MK, mevalonate kinase; MVD, mevalonate diphosphate decarboxylase; PMK, phosphomevalonate kinase; PPDS, protopanaxadiol synthase; PPTS, protopanaxatriol synthase; SE, squalene monooxygenase/epoxidase; SS, squalene synthase