Table 2 Sub-cellular localization of GCS90 after arginine (R) substitutions in the cytosolic tail.
Mutants | Cytosolic domain | Sub-cellular localization |
|---|---|---|
| Â | 6 7 10 12 | Â |
GCS90 | M T G A S R R S A R G R I K S S S L-32aa | ER |
Δ13GCS90 | M K S S S L-32aa | Golgi |
Hs10Δ13GCS90 | M A R G E R R R R A K S S S L-32aa | ER |
GCS13-XYLT35 | M T A G A S R R S A R G R I-10aa | ER + GA |
CNX11-XYLT35 | M N D R R P Q R K R P A-10aa | ER + GA |
R/L6-7GCS90 | M T G A S L L S A R G R I K S S S L-32aa | ER + punctate structures |
R/L10-12GCS90 | M T G A S R R S A L G L I K S S S L-32aa | ER + punctate structures |
R/L6-12GCS90 | M T G A S L R S A R G L I K S S S L-32aa | ER + punctate structures |
R/L6-10GCS90 | M T G A S L R S A L G R I K S S S L-32aa | ER +GA |
R/L7-12GCS90 | M T G A S R L S A R G L I K S S S L-32aa | Golgi +ER |
R/L7-10GCS90 | M T G A S R L S A L G R I K S S S L-32aa | Golgi |
R/AGCS90 | M T G A S A A S A A G A I K S S S L-32aa | Golgi |
R/LGCS90 | M T G A S L L S A L G L I K S S S L-32aa | Golgi |