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Table 1 Two-sample binomial tests for GOSlim assignments of paralogous family and singleton proteins in rice

From: Characterization of paralogous protein families in rice

GOSlim assignmenta Singletons (%) Paralogous genes (%) P-valued
Binding, otherb 3.3 6.5 <1e-5
Carbohydrate bindingc 2.7 0.6 <1e-5
DNA bindingb 4.8 8.0 <1e-5
Hydrolase activityb 7.8 12.7 <1e-5
Kinase activityc 16.0 6.2 <1e-5
Nucleotide bindingc 13.4 4.2 <1e-5
Protein binding, otherc 14.2 9.5 <1e-5
Receptor activityc 2.3 0.4 <1e-5
Transcription factor activityb 4.3 9.3 <1e-5
Catalytic activity, otherb 8.7 12.2 <1e-5
Structural molecule activityb 0.8 2.2 <1e-5
Oxygen bindingb 0.7 1.9 <1e-5
Transcription regulator activityb 1.1 2.3 <1e-5
Transporter activityb 5.0 7.0 <1e-5
Lipid bindingb 0.4 1.1 <1e-5
Molecular function, otherb 0.1 0.4 0.001
Enzyme regulator activityb 0.5 0.9 0.008
Motor activity 0.5 0.3 0.051
Transferase activity 7.0 7.7 0.095
Receptor binding 0.0 0.1 0.137
RNA binding 1.8 2.1 0.369
Translation factor activity, nucleic acid binding 0.5 0.7 0.353
Signal transducer activity 1.0 0.9 0.43
Chromatin binding 0.3 0.2 0.465
Nucleic acid binding, other 1.8 1.9 0.882
Nuclease activity 0.8 0.8 0.888
  1. a GoSlim assignment classifications were performed as described in the Materials and Methods.
  2. b Enrichment of GOSlim annotations in paralogous protein families compared to singletons.
  3. c Reduction of GOSlim annotations in paralogous protein families compared to singletons.
  4. d Benjamini and Hochberg correction for multiple testing.