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Table 1 Two-sample binomial tests for GOSlim assignments of paralogous family and singleton proteins in rice

From: Characterization of paralogous protein families in rice

GOSlim assignmenta

Singletons (%)

Paralogous genes (%)

P-valued

Binding, otherb

3.3

6.5

<1e-5

Carbohydrate bindingc

2.7

0.6

<1e-5

DNA bindingb

4.8

8.0

<1e-5

Hydrolase activityb

7.8

12.7

<1e-5

Kinase activityc

16.0

6.2

<1e-5

Nucleotide bindingc

13.4

4.2

<1e-5

Protein binding, otherc

14.2

9.5

<1e-5

Receptor activityc

2.3

0.4

<1e-5

Transcription factor activityb

4.3

9.3

<1e-5

Catalytic activity, otherb

8.7

12.2

<1e-5

Structural molecule activityb

0.8

2.2

<1e-5

Oxygen bindingb

0.7

1.9

<1e-5

Transcription regulator activityb

1.1

2.3

<1e-5

Transporter activityb

5.0

7.0

<1e-5

Lipid bindingb

0.4

1.1

<1e-5

Molecular function, otherb

0.1

0.4

0.001

Enzyme regulator activityb

0.5

0.9

0.008

Motor activity

0.5

0.3

0.051

Transferase activity

7.0

7.7

0.095

Receptor binding

0.0

0.1

0.137

RNA binding

1.8

2.1

0.369

Translation factor activity, nucleic acid binding

0.5

0.7

0.353

Signal transducer activity

1.0

0.9

0.43

Chromatin binding

0.3

0.2

0.465

Nucleic acid binding, other

1.8

1.9

0.882

Nuclease activity

0.8

0.8

0.888

  1. a GoSlim assignment classifications were performed as described in the Materials and Methods.
  2. b Enrichment of GOSlim annotations in paralogous protein families compared to singletons.
  3. c Reduction of GOSlim annotations in paralogous protein families compared to singletons.
  4. d Benjamini and Hochberg correction for multiple testing.