Systematic analysis of alternative first exons in plant genomes

BMC Plant Biology

Table 5 Functional categories (GO) significantly biased in AFE-containing clusters in Arabidopsis

	GO category	AFE containing cluster	P-value*
Enriched**	cellular physiological process	327	0
	metabolism	297	0
	nucleotide binding	65	0
	catalytic activity	27	1.52E-10
	transferase activity	104	1.35E-09
	ligase activity	25	1.73E-08
	hydrolase activity	89	1.20E-07
	ubiquitin ligase complex	13	1.24E-07
	intracellular part	259	1.94E-07
	intracellular	265	2.42E-07
	cell part	368	7.82E-06
	membrane part	37	4.80E-05
	nucleic acid binding	91	0.000128
	lyase activity	18	0.000265
	localization	51	0.000476
Depleted	triplet codon-amino acid adaptor activity	0	5.61E-06

* P-value was calculated by the hypergeometric distribution. The cutoff is 1E-5.
** "Enriched" categories refer to those containing significantly more genes (observed) than expected. "Depleted" categories refer to those containing significantly less genes (observed) than expected.