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Table 1 Selected miRNAs (including some as PHAS trigger) with differentially expression changes in response to co-infection of TYLCCNV and TYLCCNB in N. benthamiana

From: A diverse set of miRNAs responsive to begomovirus-associated betasatellite in Nicotiana benthamiana

miRNA family

Expression change (fold)*

Predicted target

References for virus response

As PHAStrigger#

References for PHAS

Conserved

     

miR160

↑7.6

Auxin response factor

[3, 8, 9]

ND

 

miR164

↑2.2

NAC domain protein

[3, 7, 9]

ND

 

miR169

↓2.0

CCAAT-binding transcription factor (CBF)

[3, 8]

ND

 

miR319

↓2.0

TCP/MYB

[8]

Yes

 

miR391

↓3.5

Putative TAS

[8]

Yes

 

miR396

↑2.4

LRR receptor-like serine/threonine-protein kinase, RLP/Pentatricopeptide repeat protein

[8]

Yes

 

miR397

↑3.5

Laccase

[8]

Yes

 

miR398

↑18.4

CSD; Zinc finger, LIM-type/Rhodanese-like

[8, 10]

Yes

 

miR482 /miR2118

↑11.0

NBS-LRR

[21]

Yes

[15, 18, 21]

miR827

↓3.1

AP2 domain-containing transcription factor/RCC1-like protein

 

Yes

 

miR4376

↓3.7

ACA

 

Yes

[22]

miR6020

↓2.0

Pentatricopeptide repeat/Glycosyl transferase

[20]

Yes

[20]

Novel

     

Nbe-miR2

↓5.9

RCC domain-containing protein

 

ND

 

Nbe-miR3

↓6.7

Not known

 

ND

 

Nbe-miR4

↓3.8

Not known

 

ND

 

Nbe-miR6

↑2.8

GH3 family protein

 

ND

 

Nbe-miR8

↑2.3

Heat shock protein binding protein

 

ND

 

Nbe-miR64

↑2.1

C2 membrane targeting protein

 

Yes

 

Nbe-miR70

↑2.1

Basic helix-loop-helix dimerisation region bHLH

 

ND

 

Nbe-miR84

↑3.4

Cyclic nucleotide gated channel

 

ND

 

Nbe-miR99

↑3.5

F-box family protein

 

Yes

 

Nbe-miR107

↑9.1

DNA repair protein radA

 

ND

 

Nbe-miR124

↑2.9

Lactoylglutathione lyase

 

ND

 

Nbe-miR129

↑2.1

Harpin-induced protein-like

 

ND

 

Nbe-miR134

↑2.8

CHP-rich zinc finger protein/F-box family protein

 

Yes

 

Nbe-miR142

↓2.0

Receptor like kinase, RLK

 

ND

 
  1. References for virus response and PHAS by previous studies were listed. A detailed list was shown as Additional file 5: Table S5.
  2. *Fold of P2/P1; #ND: not determined.