Figure 2

Predicted cluster involved in citrus peel isoprenoid and phenylpropanoid metabolism (citrus_cluster14). (A) The predicted Citrus MCL cluster 14 contained 328 nodes densely connected by 1509 edges. Genes involved in secondary metabolism (isoprenoid and phenylpropanoid), cytochrome p450/methyltransferases, lipid metabolism, hormone metabolism and signalling/transcriptional regulation were over-represented in this cluster and are coloured in purple, dark blue, orange, red and green respectively. Nodes coloured in light blue represent genes encoding proteins of miscellaneous functions (See additional files for full details). An illustration of sub-clusters for (B) putative zinc finger/E3 ubiquitin ligase protein (Cit.7748.1.S1_at) and (C) ERF13/ Ethylene response element (ERE) binding protein 1 (Cit.17124.1.S1_at, Cit.17124.1.S1_s_at, Cit.29675.1.S1_s_at, Cit.4691.1.S1_at), showing high node degree (i.e. dense connections) with many other genes within the cluster at a neighbourhood distance of 1. (D) Graph representation of cESI across the 297 tissues and conditions used in this study, with an expression specificity index greater than 1. Coloured boxes highlight the experimental conditions used for fruit peels (flavedo) of grapefruit (red) and sweet oranges (green), and for whole fruits of lemon (yellow).