Heat map of compounds identified by UPLC-MS and GC-MS in copper stress and control conditions. Samples were arranged according to a hierarchical clustering analysis (Euclidean distance), and the 47 compounds identified were grouped manually. Concentrations of each metabolite were normalized to a maximum of 1 (see Methods section). “*” and “†” indicate significant results (FDR < 5%) in the two-way ANOVA for stress and the interaction term “stress* time”, respectively. 9-HpOTrE, 9-hydroperoxy-10,12,15-octadecatrienoic acid; 13-HpOTrE, 13S-hydroperoxy-9Z,11E,15Z-octadecatrienoic acid; HpOTrE 3; oxylipin with the same m/z and raw formula as 11- or 15- hydroperoxy-9Z,11E,15Z-octadecatrienoic acid; 13-HpODE, 13-hydroperoxy-9Z,11E-octadecadienoic acid; 13-HOTrE, 13S-hydroxy-9Z,11E,15Z-octadecatrienoic acid; 13-HODE, 13-hydroxy-9Z,11E-octadecadienoic acid; 12-oxo-PDA, 12-oxophytodienoic acid; MeJA, methyl-jasmonate; PGJ2, prostaglandin J2; PGA2, prostaglandin A2, PGB2, prostaglandin B2; oxo-ETE, oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid; LTB4, leukotriene B4; GABA, γ-aminobutyric acid.