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Table 2 Genes down-regulated by CPT-induced DNA damage.

From: Transcriptomic and proteomic profiling of maize embryos exposed to camptothecin

GO Definition GB# (EST)
UniGene ID
Probe Set ID log2(R) FDR p-value Fisher p-value ANOVA Arab. ortholog gene AGI code (BLAST score)
Cell growth and division
  SMC-like domain containing protein AY111519
Zm.83602
Zm.6452.1.A1_at -1.1538 0.0190 0.0000 <0.001 At3g20350 (1e-15)
  Shugoshin-1 EU967226
Zm.96142
Zm.6790.1.A1_at -1.3230 0.0487 0.0005 0.003 At5g04320 (3e-14)
  Frizzy-like protein/WD-repeat cell cycle regulatory protein BT036099
Zm.26408
Zm.4859.1.A1_at -1.4030 0.0483 0.0004 0.002 At5g13840 (0.0)
  TPX2 AW231676
Zm.5454
Zm.5454.1.A1_at -1.6822 0.0280 0.0001 0.001 At1g03780 (8e-23)
  Cyclin IIZm (CYCA1;1) AI61499
Zm.3420
Zm.3420.1.A1_at -1.7926 0.0433 0.0003 0.002 At1g44110 (1e-141)
  Cyclin IIIZm (CYCB2) U10076
Zm.146
Zm.146.1.S1_at -2.3331 0.0438 0.0003 0.002 At1g20610 (1e-119)
  Syntaxin-related protein KNOLLE CD442886
Zm.96795
Zm.4845.2.S1_at -3.0685 0.0205 0.0001 0.001 At1g08560 (2e-95)
  Cyclin IaZm (cyclin-B1;2/CYC1BAT) AI622454
Zm.95231
Zm.4288.1.A1_at -3.2616 0.0189 0.0000 <0.001 At5g06150 (1e-71)
  Patellin-5/SEC14 cytosolic factor-like CF635836
Zm.6066
Zm.6066.1.A1_at -1.7331 0.0486 0.0004 0.003 At1g30690 (1e-114)
Cell structure
  Microtubule-associated protein RP/EB family member 3 AI586906
Zm.85067
Zm.6324.1.A1_at -1.3018 0.0483 0.0004 0.002 At5g67270 (2e-28)
Defense and stress responses
  Dirigent-like EU964079
Zm.3141
Zm.3141.1.A1_at -2.1655 0.0189 0.0000 <0.001 At5g42510 (2e-05)
  Dehydration-responsive protein RD22 U38791
Zm.265
Zm.265.1.A1_at -1.6339 0.0411 0.0002 0.002 At5g25610 (2e-26)
Membrane trafficking
  Vacuolar protein sorting-associated protein BT023983
Zm.85507
Zm.12885.1.A1_at -1.5344 0.0327 0.0002 0.001 At4g17140 (1e-157)
  Vacuolar protein sorting 13C protein-like AY107427
Zm.66893
Zm.14047.1.S1_at -1.5425 0.0190 0.0000 <0.001 At1g48090 (5e-31)
Metabolism
  Glutamate dehydrogenase D49475
Zm.44
Zm.44.1.S1_at -1.0185 0.0410 0.0002 0.001 At5g18170 (0.0)
  Endoglucanase 1 precursor CO527893
Zm.68006
Zm.4852.1.A1_at -1.1952 0.0189 0.0000 <0.001 At1g70710 (0.0)
  Nucleotide pyrophosphatase/phosphodiesterase CF646219
Zm.5570
Zm.5570.1.A1_at -1.7576 0.0204 0.0000 <0.001 At5g50400 (1e-73)
Protein processing
  Ubiquitin-conjugating enzyme BG841009
Zm.93645
Zm.14028.3.A1_at -2.6927 0.0190 0.0000 <0.001 At1g50490 (3e-65)
Signal transduction and gene expression
  RRM-containing protein SEB-4 EU972664
Zm.95189
Zm.1141.2.A1_at -1.1703 0.0486 0.0004 0.002 At1g78260 (1e-21)
  Myb-like DNA-binding domain containing protein CF244262
Zm.95733
Zm.974.1.A1_at -1.3440 0.0486 0.0004 0.002 At4g32730 (1e-26)
  Serine/arginine repetitive matrix protein 1 EU961539
Zm.85692
Zm.5999.1.A1_at -2.2585 0.0389 0.0002 0.002 At3g24550 (2e-06)
  Transcriptional regulatory protein algP EU952551
Zm.8612
Zm.1903.1.S1_at -2.3186 0.0483 0.0004 0.003 At5g10430 (1e-13)
  Homeobox transcription factor KNOTTED1 BG266135
Zm.94710
Zm.6265.1.A1_at -1.0252 0.0411 0.0002 0.001 At4g08150 (3e-98)
  VEF family protein/embryonic flower 2 AY232824
Zm.14303
Zm.14303.1.S1_at -1.0796 0.0253 0.0001 0.001 At5g51230 (4e-74)
  Rough sheath1 (RS1)/Homeo-box protein knotted-1-like L44133
Zm.95282
Zm.271.1.S1_at -1.2708 0.0313 0.0001 0.001 At4g08150 (1e-103)
  Embryogenic callus protein 98b/HMG1/2-family protein AY104178
Zm.67296
Zm.5524.1.S1_at -1.8538 0.0433 0.0003 0.002 At4g23800 (1e-144)
  Growth-regulating factor 8-like (atGRF2) AI619357
Zm.6781
Zm.6781.1.A1_at -1.4776 0.0487 0.0004 0.003 At4g37740 (2e-31)
  B3 domain containing DNA binding protein BT035134
Zm.18375
Zm.18375.1.S1_at -3.1306 0.0190 0.0000 <0.001 At3g19184 (4e-35)
  Putative receptor protein kinase (ERECTA) BE510364
Zm.7145
Zm.7145.1.A1_at -1.0473 0.0233 0.0001 <0.001 At2g26330 (0.0)
  ATROPGEF7 Rho guanyl-nucleotide exchange factor EU971244
Zm.85234
Zm.5362.1.A1_at -1.2314 0.0229 0.0001 <0.001 At5g02010 (1e-163)
Unknown
  Unknown protein EU955329
Zm.7304
Zm.7304.1.A1_x_at -1.0021 0.0324 0.0002 <0.001 At1g31335 (6e-19)
  Protein binding protein/ankyrin repeat family protein/hox1a EU957633
Zm.94760
Zm.6575.1.A1_at -1.0453 0.0189 0.0000 <0.001 At5g14230 (0.0)
  Unknown protein EE289957
Zm.5555
Zm.5555.1.S1_at -1.0503 0.0280 0.0001 0.001 At2g16270 (2e-06)
  Unknown protein EU966578
Zm.1003
Zm.14948.1.A1_at -1.0540 0.0486 0.0004 0.002 At5g44040 (8e-31)
  Zinc finger (C3HC4-type RING finger)-like protein BT033558
Zm.85528
Zm.4717.1.A1_at -1.1443 0.0244 0.0001 0.001 At5g60710 (3e-34)
  Lipid binding protein BM380917
Zm.3374
Zm.3374.1.S1_at -1.1558 0.0312 0.0001 0.001 At3g53980 (4e-33)
  Histidine kinase-like ATPases superfamily BT062141
Zm.2931
Zm.2931.1.A1_at -1.1903 0.0271 0.0001 0.001 At5g50780 (0.0)
  Unknown protein AY108387
Zm.1851
Zm.1851.1.A1_at -1.3130 0.0486 0.0004 0.002 At3g15560 (4e-06)
  Alpha-amylase inhibitor, lipid transfer & seed storage protein EU966009
Zm.84843
Zm.1477.1.S1_at -1.3289 0.0233 0.0001 0.001 At1g62790 (1e-20)
  Uncharacterized plant-specific domain TIGR01568 protein EU964402
Zm.4518
Zm.4518.1.A1_at -1.3515 0.0271 0.0001 0.001 At1g31810 (3e-12)
  Unknown protein CB331155
Zm.14601
Zm.14601.1.A1_at -1.4546 0.0424 0.0003 0.002 At1g65710 (7e-30)
  Putative mitochondrial glycoprotein CN071241
Zm.10190
Zm.10190.1.S1_at -1.5186 0.0313 0.0001 0.001 At3g55605 (2e-35)
  Unknown protein EU953101
Zm.7304
Zm.7304.2.S1_x_at -1.7155 0.0190 0.0000 0.001 At1g31335 (2e-18)
  Glycin-rich protein 3 (ZmGrp3) Y07781
Zm.81016
Zm.106.1.A1_at -1.8099 0.0478 0.0003 0.002 At5g46730 (3e-48)
  Unknown protein/Armadillo-type fold CO523236
Zm.17093
Zm.17093.1.S1_at -2.0104 0.0487 0.0004 0.003 At4g15830 (1e-65)
  Unknown protein EU949556
Zm.6891
Zm.6891.1.S1_at -2.1106 0.0205 0.0001 0.001 At1g16630 (9e-14)
  Unknown protein EU952572
Zm.12124
Zm.12124.1.A1_at -2.1345 0.0313 0.0001 0.001 At1g16610 (3e-04)
  Unknown protein BT033638
Zm.74351
Zm.5168.1.A1_at -2.1775 0.0098 0.0000 <0.001 At2g30820 (2e-33)
  Unknown protein EU947738
Zm.13423
Zm.13423.1.A1_at -2.4249 0.0173 0.0000 <0.001 nd
  Unknown protein AI395973
Zm.6726
Zm.6726.1.S1_x_at -2.5460 0.0419 0.0003 <0.001 At5g16250 (1e-48)
  Unknown protein EU966355
Zm.4821
Zm.4821.1.S1_at -2.5761 0.0313 0.0001 0.001 At2g29210 (4e-05)
  Glycine rich protein 3 CK371522
Zm.98965
Zm.17547.1.S1_at -2.7476 0.0233 0.0001 0.001 At5g46730 (2e-50)
  Unknown protein AY112394
Zm.6726
Zm.6726.2.A1_at -3.0188 0.0189 0.0000 0.002 At5g16250 (3e-41)
  Unknown protein CF627668
Zm.17534
Zm.17534.2.S1_at -3.7711 0.0271 0.0001 0.001 At5g36710 (1e-38)
  1. GB#, maize EST accession number in GenBank database. UniGene ID code; Probe set ID in Affymetrix chip; Affymetrix chip hybridization parameters: R ≤ 0.5 and FDR ≤ 0.05.