Table 2 Genes down-regulated by CPT-induced DNA damage.
From: Transcriptomic and proteomic profiling of maize embryos exposed to camptothecin
GO | Definition | GB# (EST) UniGene ID | Probe Set ID | log2(R) | FDR | p-value Fisher | p-value ANOVA | Arab. ortholog gene AGI code (BLAST score) |
|---|---|---|---|---|---|---|---|---|
Cell growth and division | ||||||||
| Â | SMC-like domain containing protein | AY111519 Zm.83602 | Zm.6452.1.A1_at | -1.1538 | 0.0190 | 0.0000 | <0.001 | At3g20350 (1e-15) |
| Â | Shugoshin-1 | EU967226 Zm.96142 | Zm.6790.1.A1_at | -1.3230 | 0.0487 | 0.0005 | 0.003 | At5g04320 (3e-14) |
| Â | Frizzy-like protein/WD-repeat cell cycle regulatory protein | BT036099 Zm.26408 | Zm.4859.1.A1_at | -1.4030 | 0.0483 | 0.0004 | 0.002 | At5g13840 (0.0) |
| Â | TPX2 | AW231676 Zm.5454 | Zm.5454.1.A1_at | -1.6822 | 0.0280 | 0.0001 | 0.001 | At1g03780 (8e-23) |
| Â | Cyclin IIZm (CYCA1;1) | AI61499 Zm.3420 | Zm.3420.1.A1_at | -1.7926 | 0.0433 | 0.0003 | 0.002 | At1g44110 (1e-141) |
| Â | Cyclin IIIZm (CYCB2) | U10076 Zm.146 | Zm.146.1.S1_at | -2.3331 | 0.0438 | 0.0003 | 0.002 | At1g20610 (1e-119) |
| Â | Syntaxin-related protein KNOLLE | CD442886 Zm.96795 | Zm.4845.2.S1_at | -3.0685 | 0.0205 | 0.0001 | 0.001 | At1g08560 (2e-95) |
| Â | Cyclin IaZm (cyclin-B1;2/CYC1BAT) | AI622454 Zm.95231 | Zm.4288.1.A1_at | -3.2616 | 0.0189 | 0.0000 | <0.001 | At5g06150 (1e-71) |
| Â | Patellin-5/SEC14 cytosolic factor-like | CF635836 Zm.6066 | Zm.6066.1.A1_at | -1.7331 | 0.0486 | 0.0004 | 0.003 | At1g30690 (1e-114) |
Cell structure | ||||||||
| Â | Microtubule-associated protein RP/EB family member 3 | AI586906 Zm.85067 | Zm.6324.1.A1_at | -1.3018 | 0.0483 | 0.0004 | 0.002 | At5g67270 (2e-28) |
Defense and stress responses | ||||||||
| Â | Dirigent-like | EU964079 Zm.3141 | Zm.3141.1.A1_at | -2.1655 | 0.0189 | 0.0000 | <0.001 | At5g42510 (2e-05) |
| Â | Dehydration-responsive protein RD22 | U38791 Zm.265 | Zm.265.1.A1_at | -1.6339 | 0.0411 | 0.0002 | 0.002 | At5g25610 (2e-26) |
Membrane trafficking | ||||||||
| Â | Vacuolar protein sorting-associated protein | BT023983 Zm.85507 | Zm.12885.1.A1_at | -1.5344 | 0.0327 | 0.0002 | 0.001 | At4g17140 (1e-157) |
| Â | Vacuolar protein sorting 13C protein-like | AY107427 Zm.66893 | Zm.14047.1.S1_at | -1.5425 | 0.0190 | 0.0000 | <0.001 | At1g48090 (5e-31) |
Metabolism | ||||||||
| Â | Glutamate dehydrogenase | D49475 Zm.44 | Zm.44.1.S1_at | -1.0185 | 0.0410 | 0.0002 | 0.001 | At5g18170 (0.0) |
| Â | Endoglucanase 1 precursor | CO527893 Zm.68006 | Zm.4852.1.A1_at | -1.1952 | 0.0189 | 0.0000 | <0.001 | At1g70710 (0.0) |
| Â | Nucleotide pyrophosphatase/phosphodiesterase | CF646219 Zm.5570 | Zm.5570.1.A1_at | -1.7576 | 0.0204 | 0.0000 | <0.001 | At5g50400 (1e-73) |
Protein processing | ||||||||
| Â | Ubiquitin-conjugating enzyme | BG841009 Zm.93645 | Zm.14028.3.A1_at | -2.6927 | 0.0190 | 0.0000 | <0.001 | At1g50490 (3e-65) |
Signal transduction and gene expression | ||||||||
| Â | RRM-containing protein SEB-4 | EU972664 Zm.95189 | Zm.1141.2.A1_at | -1.1703 | 0.0486 | 0.0004 | 0.002 | At1g78260 (1e-21) |
| Â | Myb-like DNA-binding domain containing protein | CF244262 Zm.95733 | Zm.974.1.A1_at | -1.3440 | 0.0486 | 0.0004 | 0.002 | At4g32730 (1e-26) |
| Â | Serine/arginine repetitive matrix protein 1 | EU961539 Zm.85692 | Zm.5999.1.A1_at | -2.2585 | 0.0389 | 0.0002 | 0.002 | At3g24550 (2e-06) |
| Â | Transcriptional regulatory protein algP | EU952551 Zm.8612 | Zm.1903.1.S1_at | -2.3186 | 0.0483 | 0.0004 | 0.003 | At5g10430 (1e-13) |
| Â | Homeobox transcription factor KNOTTED1 | BG266135 Zm.94710 | Zm.6265.1.A1_at | -1.0252 | 0.0411 | 0.0002 | 0.001 | At4g08150 (3e-98) |
| Â | VEF family protein/embryonic flower 2 | AY232824 Zm.14303 | Zm.14303.1.S1_at | -1.0796 | 0.0253 | 0.0001 | 0.001 | At5g51230 (4e-74) |
| Â | Rough sheath1 (RS1)/Homeo-box protein knotted-1-like | L44133 Zm.95282 | Zm.271.1.S1_at | -1.2708 | 0.0313 | 0.0001 | 0.001 | At4g08150 (1e-103) |
| Â | Embryogenic callus protein 98b/HMG1/2-family protein | AY104178 Zm.67296 | Zm.5524.1.S1_at | -1.8538 | 0.0433 | 0.0003 | 0.002 | At4g23800 (1e-144) |
| Â | Growth-regulating factor 8-like (atGRF2) | AI619357 Zm.6781 | Zm.6781.1.A1_at | -1.4776 | 0.0487 | 0.0004 | 0.003 | At4g37740 (2e-31) |
| Â | B3 domain containing DNA binding protein | BT035134 Zm.18375 | Zm.18375.1.S1_at | -3.1306 | 0.0190 | 0.0000 | <0.001 | At3g19184 (4e-35) |
| Â | Putative receptor protein kinase (ERECTA) | BE510364 Zm.7145 | Zm.7145.1.A1_at | -1.0473 | 0.0233 | 0.0001 | <0.001 | At2g26330 (0.0) |
| Â | ATROPGEF7 Rho guanyl-nucleotide exchange factor | EU971244 Zm.85234 | Zm.5362.1.A1_at | -1.2314 | 0.0229 | 0.0001 | <0.001 | At5g02010 (1e-163) |
Unknown | ||||||||
| Â | Unknown protein | EU955329 Zm.7304 | Zm.7304.1.A1_x_at | -1.0021 | 0.0324 | 0.0002 | <0.001 | At1g31335 (6e-19) |
| Â | Protein binding protein/ankyrin repeat family protein/hox1a | EU957633 Zm.94760 | Zm.6575.1.A1_at | -1.0453 | 0.0189 | 0.0000 | <0.001 | At5g14230 (0.0) |
| Â | Unknown protein | EE289957 Zm.5555 | Zm.5555.1.S1_at | -1.0503 | 0.0280 | 0.0001 | 0.001 | At2g16270 (2e-06) |
| Â | Unknown protein | EU966578 Zm.1003 | Zm.14948.1.A1_at | -1.0540 | 0.0486 | 0.0004 | 0.002 | At5g44040 (8e-31) |
| Â | Zinc finger (C3HC4-type RING finger)-like protein | BT033558 Zm.85528 | Zm.4717.1.A1_at | -1.1443 | 0.0244 | 0.0001 | 0.001 | At5g60710 (3e-34) |
| Â | Lipid binding protein | BM380917 Zm.3374 | Zm.3374.1.S1_at | -1.1558 | 0.0312 | 0.0001 | 0.001 | At3g53980 (4e-33) |
| Â | Histidine kinase-like ATPases superfamily | BT062141 Zm.2931 | Zm.2931.1.A1_at | -1.1903 | 0.0271 | 0.0001 | 0.001 | At5g50780 (0.0) |
| Â | Unknown protein | AY108387 Zm.1851 | Zm.1851.1.A1_at | -1.3130 | 0.0486 | 0.0004 | 0.002 | At3g15560 (4e-06) |
| Â | Alpha-amylase inhibitor, lipid transfer & seed storage protein | EU966009 Zm.84843 | Zm.1477.1.S1_at | -1.3289 | 0.0233 | 0.0001 | 0.001 | At1g62790 (1e-20) |
| Â | Uncharacterized plant-specific domain TIGR01568 protein | EU964402 Zm.4518 | Zm.4518.1.A1_at | -1.3515 | 0.0271 | 0.0001 | 0.001 | At1g31810 (3e-12) |
| Â | Unknown protein | CB331155 Zm.14601 | Zm.14601.1.A1_at | -1.4546 | 0.0424 | 0.0003 | 0.002 | At1g65710 (7e-30) |
| Â | Putative mitochondrial glycoprotein | CN071241 Zm.10190 | Zm.10190.1.S1_at | -1.5186 | 0.0313 | 0.0001 | 0.001 | At3g55605 (2e-35) |
| Â | Unknown protein | EU953101 Zm.7304 | Zm.7304.2.S1_x_at | -1.7155 | 0.0190 | 0.0000 | 0.001 | At1g31335 (2e-18) |
| Â | Glycin-rich protein 3 (ZmGrp3) | Y07781 Zm.81016 | Zm.106.1.A1_at | -1.8099 | 0.0478 | 0.0003 | 0.002 | At5g46730 (3e-48) |
| Â | Unknown protein/Armadillo-type fold | CO523236 Zm.17093 | Zm.17093.1.S1_at | -2.0104 | 0.0487 | 0.0004 | 0.003 | At4g15830 (1e-65) |
| Â | Unknown protein | EU949556 Zm.6891 | Zm.6891.1.S1_at | -2.1106 | 0.0205 | 0.0001 | 0.001 | At1g16630 (9e-14) |
| Â | Unknown protein | EU952572 Zm.12124 | Zm.12124.1.A1_at | -2.1345 | 0.0313 | 0.0001 | 0.001 | At1g16610 (3e-04) |
| Â | Unknown protein | BT033638 Zm.74351 | Zm.5168.1.A1_at | -2.1775 | 0.0098 | 0.0000 | <0.001 | At2g30820 (2e-33) |
| Â | Unknown protein | EU947738 Zm.13423 | Zm.13423.1.A1_at | -2.4249 | 0.0173 | 0.0000 | <0.001 | nd |
| Â | Unknown protein | AI395973 Zm.6726 | Zm.6726.1.S1_x_at | -2.5460 | 0.0419 | 0.0003 | <0.001 | At5g16250 (1e-48) |
| Â | Unknown protein | EU966355 Zm.4821 | Zm.4821.1.S1_at | -2.5761 | 0.0313 | 0.0001 | 0.001 | At2g29210 (4e-05) |
| Â | Glycine rich protein 3 | CK371522 Zm.98965 | Zm.17547.1.S1_at | -2.7476 | 0.0233 | 0.0001 | 0.001 | At5g46730 (2e-50) |
| Â | Unknown protein | AY112394 Zm.6726 | Zm.6726.2.A1_at | -3.0188 | 0.0189 | 0.0000 | 0.002 | At5g16250 (3e-41) |
| Â | Unknown protein | CF627668 Zm.17534 | Zm.17534.2.S1_at | -3.7711 | 0.0271 | 0.0001 | 0.001 | At5g36710 (1e-38) |