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Table 3 Selected GO biological process terms over- and underrepresented among genes called up and down.

From: Transcriptional profiles underlying parent-of-origin effects in seeds of Arabidopsis thaliana

sample

GO term

no. (%) in sample

no. (%) in all genes

P-value

bold = underrepresented

all genes in experiment

n = 11,091 annotated

    

2xX4x down

n = 71 annotated

response to stimulus

15(21.12)

817(7.3)

0.00159

 

regulation of transcription, DNA-dependent

8(11.26)

374(3.37)

0.0181

2xX6x up

n = 228 annotated

cell wall organization and biogenesis

8 (3.5)

80 (0.72)

0.0371

 

inorganic anion transport

4(1.75)

20(0.18)

0.0483

2xX6x down

n = 302 annotated

microtubule-based movement

9(2.98)

26(0.23)

2.56 e-06

 

regulation of cell cycle

7(2.31)

38(0.34)

0.00426

 

steroid metabolic process

4(1.32)

18(0.16)

0.0373

fis1X2x up

n = 304 annotated

carbohydrate metabolic process

27(8.88)

351(3.16)

7.88 e-06

fis1x2x down

n = 541 annotated

biosynthetic process

16(2.77)

773(6.96)

0.0342

 

electron transport

33(6.09)

352(3.17)

0.0295

 

regulation of biological process

63(11.64)

838(7.55)

0.0342

 

regulation of cell cycle

8(1.47)

38(0.34)

0.0345

 

sequestering of lipid

4(0.73)

8(0.72)

0.0342

 

response to chemical stimulus

31(5.73)

348(3.13)

0.0399

4x X 2x up

n = 219 annotated

cellular process

44(20.09)

3665(33.0)

0.0141

6xX2x up

n = 554 annotated

defense response

30(5.41)

189(1.70)

8.11 e-09

 

response to stimulus

67(12.09)

817(7.36)

0.00345

 

response to starvation

5(0.9)

14(0.13)

0.019

 

macromolecule metabolic process

73(13.17)

2300(20.74)

0.00246

6xX2x down

n = 697 annotated

translation

41(5.88)

276(2.49)

2,76 e-06

 

macromolecule biosynthetic process

48(6.88)

380(3.42)

5.57 e-05

 

macromolecule metabolic process

185(26.54)

2300(20.73)

0.00551

 

DNA replication initiation

4(0.57)

7(0.06)

0.0207

 

transcription factor import into nucleus

3(0.43)

4(0.04)

0.0367

 

DNA metabolic process

29(4.16)

168(1.5)

2.76 e-06

 

nucleosome assembly

11(1.57)

28(0.25)

5.57 e-05

 

chromatin assembly and disassembly

12(1.72)

38(0.34)

0.00019

 

organelle organization and biogenesis

42(6.02)

291(2.62)

2.76 e-06

 

cellular component organization and biogenesis

63(9.03)

618(5.57)

0.00282

 

microtubule-based movement

7(1.0)

26(0.23)

0.0358

  1. The GOstat tool (http://gostat.wehi.edu.au/; Beissbarth and Speed, 2004) was used to identify GO biological process terms significantly (P < 0.05) over- and underrepresented among genes called up and down. P-values were adjusted using the Benjamini and Hochberg correction for multiple testing. Each list was compared with the set of all genes called present in the experiment.
  2. n = number of genes in each list with GO biological process annotation.