Figure 1From: Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell culturesBiosynthetic pathway from tyrosine to sanguinarine. Biosynthesis of sanguinarine from tyrosine. Enzymes for which cognate cDNAs have been isolated are shown in black. Abbreviations: TYDC, tyrosine/dopa decarboxylase; NCS, norcoclaurine synthase; 6OMT, (S)-norcoclaurine 6-O-methyltransferase; CNMT, (S)-coclaurine N-methyltransferase; NMCH, (S)-N-methylcoclaurine 3'-hydroxylase; 4'OMT, (S)-3'-hdroxy-N-methylcoclaurine 4'-O-methyltransferase; BBE, berberine bridge enzyme; CheSyn, cheilanthifoline synthase; StySyn, stylopine synthase; TNMT, tetrahydroprotoberberine N-methyltransferase; MSH, methylstylopine hydroxylase; P6 H, protopine 6-hydroxylase; DBOX, dihydrobenzophenanthridine oxidase. StySyn and CheSyn cDNAs were functionally characterized in plant species other than opium poppy.Back to article page